When the Arizona Cardinals vs Buffalo Bills clash takes place, football fans anticipate not only a compelling contest but also a deep dive into individual performances—because in NFL games, the story often lies within the numbers. This article offers a comprehensive breakdown of player stats, head-to-head insights, standout performances, and key takeaways from their match. Whether you’re tracking quarterbacks, running backs, receivers, or defensive stars, this piece will serve as your go-to reference for the Arizona Cardinals vs Buffalo Bills match player stats and what they tell us about the game’s outcome and implications.
Historical & Head-to-Head Context
Before jumping into the numbers from a specific game, it’s important to set the stage with some historical context. Across all meetings, the Arizona Cardinals have a 5–8 record against the Bills, giving Buffalo a slight edge in their head-to-head matchup. StatMuse That historical edge sets a tone: when these two teams meet, Buffalo has often had the upper hand, though not overwhelmingly so.
When they face off, patterns emerge. The Bills tend to exploit defensive weaknesses, particularly in passing defense, while Arizona often leans on explosiveness in the open field. In many matchups, the game has been decided not just by team strategy but by which players execute their roles at a high level. Therefore, comparing the player stats—yards, touchdowns, sacks, tackles—is vital to understanding who won the day.
Game Recap & Key Statistical Highlights
Let’s anchor our analysis on a specific recent meeting: in September 2024, Buffalo defeated Arizona 34–28. buffalobills.com+2ESPN.com+2 This matchup illustrates how closely contested games between these teams can be.
Offensive Leaders & Quarterbacks
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Josh Allen (Buffalo Bills) 
 Allen was stellar in that game, passing for 232 yards and 2 passing touchdowns, while also contributing on the ground with 41 rushing yards and 2 rushing touchdowns. buffalobills.com His dual-threat ability made him a constant danger to Arizona’s defense.
 Allen’s performance underscores one of his strengths: the ability to extend plays with his legs, not just with his arm.
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Kyler Murray (Arizona Cardinals) 
 On the Arizona side, Murray completed 21 of 31 passes for 162 yards and added 57 rushing yards. ESPN.com+1 While his passing numbers weren’t eye-popping in that game, his mobility kept pressure off the Cardinals’ ground game and forced defensive adjustments.
Running Backs & Receiving Threats
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James Cook (Bills) 
 Cook ran for 71 yards and also chipped in in the receiving game, giving Buffalo balance in their attack. buffalobills.com
 His contributions show how having a stable dual-threat back helps open up both run and pass options.
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Greg Dortch & Other Cardinals Receivers 
 Greg Dortch, for example, had 6 receptions for 47 yards. ESPN.com Arizona tried to mix shorter connections and rely on Murray’s legs to complement the passing game.
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Deep Threats & Big Plays 
 Buffalo’s receivers, like Mack Hollins and Khalil Shakir, each had touchdown catches (11 yards apiece). USA TODAY+1 These bursts through the secondary helped shift momentum in Buffalo’s favor.
Defensive & Special Teams Highlights
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Sacks, Tackles & Disruption 
 Buffalo’s defense recorded 3 sacks (Greg Rousseau among the leaders) and forced a fumble that turned into a scoring drive. buffalobills.com On the boards, Arizona’s defense also managed to get pressure, but the Bills’ offense was better at evading and responding.
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Special Teams & Non-Offensive Scores 
 A telling moment was Arizona’s 96-yard kickoff return by DeeJay Dallas, which set up a two-point conversion to reduce the margin to one. USA TODAY+1 Shows how special teams can shift a close game’s momentum.
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Time of Possession & Efficiency 
 In that game, Buffalo won the yardage battle (352 yards to Arizona’s 270) and had a slight edge in first downs and third-down efficiency (though both teams had their struggles). ESPN.com+1 Even when Arizona had moments of offensive success, Buffalo’s defensive consistency held key drives.
Player Performance Trends & What They Tell Us
Looking at these stats, several trends emerge:
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Quarterback dual-threats matter — Josh Allen’s ability to run as well as pass stretched Arizona’s defense, forcing them to guard against both. Kyler Murray’s mobility helps Arizona somewhat, but when held in check, the Cardinals often struggle to sustain drives. 
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Balance at running back is key — James Cook’s dual role and Arizona’s lesser success running the ball prevented the Cardinals from controlling tempo as much as they might have hoped. 
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Explosive plays tilt momentum — Buffalo’s big passing touchdowns and Arizona’s special teams return show how single plays can swing the game. 
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Defense and turnovers decide close games — While both offenses had their moments, Buffalo’s defensive plays (sacks, forcing turnovers) and better execution in the fourth quarter sealed the win. 
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Special teams can’t be ignored — The kickoff return by Arizona kept them alive; in tight games, every yard gained or lost in special teams is amplified. 
Conclusion
The Arizona Cardinals vs Buffalo Bills matchups often come down to execution, individual brilliance, and the interplay of offense, defense, and special teams. In the example game of September 2024, Buffalo’s Josh Allen showcased why he’s one of the league’s most dangerous quarterbacks: capable in both passing and running, and adept at making clutch plays. Meanwhile, Arizona leaned on Kyler Murray’s mobility and occasional big receptions but couldn’t match Buffalo’s balance and depth.
When writing about player stats in these matchups, the key is not just reporting yardage and touchdowns—but interpreting how those numbers shaped the flow of the game. Who made the critical play? Which unit (offense, defense, special teams) won the battle in pivotal moments? That’s what separates a stats recap from a compelling narrative.
In future matchups, watching whether Arizona can contain Allen’s legs, whether Buffalo’s defense can pressure Murray, and whether Arizona’s ground game can gain traction could be the deciding factors. These individual stats aren’t just numbers—they are clues to which team executed their game plan better under pressure.
FAQ (Frequently Asked Questions)
Q1: What are “player stats” in NFL games?
Player stats refer to the numerical measures of how well individual players performed—things like passing yards, rushing yards, receiving yards, touchdowns, interceptions, tackles, sacks, forced fumbles, and more. These help quantify a player’s contribution to the game.
Q2: Why are Arizona Cardinals vs Buffalo Bills matchups interesting statistically?
Because both teams tend to have explosive offense and key playmakers, their games often feature high-variance plays. By comparing player stats, we can see which side’s strengths asserted themselves: quarterback mobility, explosive passing, defensive disruption, or special teams.
Q3: Does a quarterback with fewer passing yards always lose?
Not necessarily. A quarterback’s impact isn’t just passing yards. If he contributes with rushing touchdowns, avoids turnovers, sustains drives, or makes clutch throws, he can influence the outcome even with lower yardage.
Q4: How much do turnovers and special teams influence close NFL games?
A lot. In tight games (like 34–28 above), a forced fumble, interception, or long return can flip momentum. Player stats in those areas—even if they look small (like 1 forced fumble or 1 kickoff return)—often turn into the difference.
Q5: How should I use this article (and similar ones) to improve Google ranking?
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Make sure your final article includes the target keywords (e.g. “Arizona Cardinals vs Buffalo Bills match player stats”) in the title, heading, and in naturally woven text. 
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Use subheadings and structure (H2, H3) so search engines can parse the content. 
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Add internal/external links to credible sources (e.g. MLB/NFL official stats, team pages). 
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Enrich with relevant stats tables or visualizations (if possible). 
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Keep content fresh—update stats or link to latest games, especially when they play again. 

